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Published on: October 31, 2010
High-Yield Birth-Cohort Hepatitis C Virus Screening and Linkage to Care Among Underserved African Americans, Atlanta,
Lesley S Miller1, Francois Rollin1, Shelly-Ann Fluker1
1Emory University School of Medicine, Department of Medicine, Division of General Medicine and Geriatrics, Atlanta, GA.
Insights
Hepatitis C virus (HCV) screening identified previously undiagnosed infections in baby boomers and African Americans. The TILT-C program effectively linked these patients to care, highlighting the need for targeted screening in high-risk populations.
Area of Science:
- Hepatology
- Public Health
- Infectious Diseases
Background:
- Hepatitis C virus (HCV) disproportionately affects baby boomers and African Americans.
- Targeted screening and linkage to care are crucial for managing HCV infection in at-risk populations.
Purpose of the Study:
- To assess the feasibility and effectiveness of the Internal Medicine Trainees Identifying and Linking to Treatment for Hepatitis C (TILT-C) initiative.
- To identify previously undiagnosed chronic Hepatitis C virus infections in a primarily African American baby boomer population and link them to care.
Main Methods:
- Implementation of an electronic medical record prompt and educational sessions to increase HCV screening.
- Tracking of testing outcomes and linkage to care for HCV-positive patients.
- Routine HCV screening conducted at 34 U.S. sites as part of a broader initiative.
Main Results:
- Of 2,894 patients screened, 201 (6.9%) tested positive for HCV antibodies.
- Men exhibited a significantly higher prevalence of HCV infection (9.7%) compared to women (5.3%).
- 120 of 124 HCV RNA-positive patients attended their initial care appointment.
Conclusions:
- The TILT-C screening program demonstrated feasibility and effectiveness in detecting undiagnosed HCV infections.
- The high prevalence in the studied population underscores the necessity of aggressive screening for Hepatitis C virus in similar demographics.
- Effective linkage to care was achieved, improving patient outcomes for those diagnosed with HCV.
Objective:
Hepatitis C virus (HCV) infection disproportionately affects certain populations, including those born between 1945 and 1965 (i.e., baby boomers) and African Americans. As part of the Hepatitis Testing and Linkage to Care initiative, which promoted hepatitis B and hepatitis C screening, posttest counseling, and linkage to care at 34 U.S. sites, we conducted routine HCV screening to identify previously undiagnosed, primarily African American baby boomers with chronic hepatitis C infection and link them to care.
Methods:
We launched the Internal Medicine Trainees Identifying and Linking to Treatment for Hepatitis C (TILT-C) initiative at the Grady Memorial Hospital Primary Care Center and Grady Liver Clinic in Atlanta, Georgia, in October 2012, and present results from the first year. TILT-C faculty implemented an electronic medical record prompt and conducted educational sessions to boost HCV screening. A project coordinator tracked testing outcomes and linked HCV-positive patients to care.
Results:
Of 2,894 patients tested for anti-HCV, 201 (6.9%) tested positive. Men had a significantly higher (p<0.001) prevalence of HCV infection than women, with 106 of 1,091 (9.7%) men compared with 95 of 1,803 (5.3%) women testing anti-HCV positive. A total of 174 of 201 (86.6%) anti-HCV-positive patients received HCV ribonucleic acid (RNA) testing. Of 124 patients with a positive HCV RNA test, 122 were referred to care and 120 attended the first appointment.
Conclusion:
The TILT-C screening program was feasible and effective in detecting previously undiagnosed HCV infection and linking patients to care. The unexpectedly high prevalence of HCV infection in this primarily African American, baby boomer population underscores the need for aggressive HCV screening efforts in similar populations.
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