High-Yield Birth-Cohort Hepatitis C Virus Screening and Linkage to Care Among Underserved African Americans, Atlanta,

Lesley S Miller1, Francois Rollin1, Shelly-Ann Fluker1

  • 1Emory University School of Medicine, Department of Medicine, Division of General Medicine and Geriatrics, Atlanta, GA.

Insights

Hepatitis C virus (HCV) screening identified previously undiagnosed infections in baby boomers and African Americans. The TILT-C program effectively linked these patients to care, highlighting the need for targeted screening in high-risk populations.

Area of Science:

  • Hepatology
  • Public Health
  • Infectious Diseases

Background:

  • Hepatitis C virus (HCV) disproportionately affects baby boomers and African Americans.
  • Targeted screening and linkage to care are crucial for managing HCV infection in at-risk populations.

Purpose of the Study:

  • To assess the feasibility and effectiveness of the Internal Medicine Trainees Identifying and Linking to Treatment for Hepatitis C (TILT-C) initiative.
  • To identify previously undiagnosed chronic Hepatitis C virus infections in a primarily African American baby boomer population and link them to care.

Main Methods:

  • Implementation of an electronic medical record prompt and educational sessions to increase HCV screening.
  • Tracking of testing outcomes and linkage to care for HCV-positive patients.
  • Routine HCV screening conducted at 34 U.S. sites as part of a broader initiative.

Main Results:

  • Of 2,894 patients screened, 201 (6.9%) tested positive for HCV antibodies.
  • Men exhibited a significantly higher prevalence of HCV infection (9.7%) compared to women (5.3%).
  • 120 of 124 HCV RNA-positive patients attended their initial care appointment.

Conclusions:

  • The TILT-C screening program demonstrated feasibility and effectiveness in detecting undiagnosed HCV infections.
  • The high prevalence in the studied population underscores the necessity of aggressive screening for Hepatitis C virus in similar demographics.
  • Effective linkage to care was achieved, improving patient outcomes for those diagnosed with HCV.
Abstract