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Updated: Mar 21, 2026

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy
Published on: May 28, 2021
Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in
C A Bader1, E A Carter2, A Safitri2
1Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences/Sansom Institute for Health Research, University of South Australia, Adelaide, Australia. sally.plush@unisa.edu.au.
Abstract:
Fourier transform infrared (FTIR) microspectroscopy and confocal imaging have been used to demonstrate that the neutral rhenium(i) tricarbonyl 1,10-phenanthroline complex bound to 4-cyanophenyltetrazolate as the ancillary ligand is able to localise in regions with high concentrations of polar lipids such as phosphatidylethanolamine (PE), sphingomyelin, sphingosphine and lysophosphatidic acid (LPA) in mammalian adipocytes.
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