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Updated: Mar 21, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Atrial septal defect closure with left ventricular dysfunction
Victor-Xavier Tadros1, Anita W Asgar
1Interventional Cardiology, Department of Medicine, Montreal Heart Institute, Université de Montréal, Montréal, QC, Canada.
Insights
Transcatheter closure of atrial septal defects (ASD) is standard, but carries risks in adults with left ventricular dysfunction. This review covers managing ASD closure in these patients to minimize complications.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Interventional Cardiology
Background:
- Atrial septal defects (ASD) are common adult congenital heart diseases, often causing left-to-right shunts.
- Undiagnosed ASDs can lead to significant hemodynamic changes and symptoms in adulthood.
- Transcatheter ASD closure is preferred, but carries risks in patients with left ventricular (LV) dysfunction due to pressure changes.
Purpose of the Study:
- To review clinical aspects of transcatheter ASD closure in adults with LV dysfunction.
- To discuss risk evaluation methods for these complex patients.
- To outline strategies for minimizing complications during ASD closure.
Main Methods:
- Review of current literature on transcatheter ASD closure.
- Analysis of hemodynamic implications in patients with LV dysfunction.
- Discussion of risk stratification and management strategies.
Main Results:
- Transcatheter ASD closure in LV dysfunction requires careful patient selection and monitoring.
- Acute hemodynamic shifts can precipitate complications in vulnerable patients.
- Pre-procedural risk assessment and tailored closure strategies are crucial.
Conclusions:
- Transcatheter ASD closure is feasible in select patients with LV dysfunction.
- Minimizing complications involves comprehensive risk assessment and individualized management.
- Further research may refine optimal strategies for this patient population.
Abstract:
Atrial septal defects are one of the most common congenital heart diseases in adults that may result in significant left to right shunt. Secundum atrial septal defects can remain unrecognised until adult age and cause haemodynamic changes with or without symptoms. Transcatheter ASD closure is the gold standard; however, in those patients with left ventricular dysfunction there may be increased risk of complications due to acute changes in left-sided pressures. In this review, we discuss the clinical aspects of ASD closure in the setting of LV dysfunction and discuss methods to evaluate risk and strategies to minimise complications.
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