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[A case of donovanosis acquired in France]

I Okhremchuk1, E Marmottant2, S Abed2

  • 1Service d'anatomie et cytologie pathologiques, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France; Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.

Annales De Dermatologie Et De Venereologie
|May 14, 2016
PubMed
Abstract

Insights

Donovanosis, a genital infection, was diagnosed in metropolitan France, challenging its tropical prevalence. Prompt azithromycin treatment led to rapid ulcer healing, highlighting effective management.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Genitourinary Medicine

Background:

  • Donovanosis (granuloma inguinale) is a sexually transmitted infection caused by Klebsiella granulomatis.
  • Typically prevalent in tropical regions, it affects the genital area.

Observation:

  • A case of donovanosis was reported in metropolitan France.
  • A 47-year-old man presented with a month-long, painless glans ulceration.
  • No recent travel history was reported, suggesting local transmission.

Findings:

  • Skin biopsy confirmed Donovan bodies within macrophages.
  • Unprotected sexual contact in France was identified as the likely transmission route.
  • Azithromycin treatment resulted in rapid clinical improvement within 7 days.

Implications:

  • This case highlights the potential for donovanosis occurrence outside tropical zones.
  • It underscores the importance of considering donovanosis in genital ulcer differential diagnoses, even in non-endemic areas.
  • Successful treatment with azithromycin confirms its efficacy for donovanosis.
Keywords:
Autochthonous infectionDonovanoseDonovanosisFranceGranuloma inguinaleGranulome inguinalInfection autochtone

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