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Cholesterol Efflux Assay
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E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro

Ni Li1, Xiao Wang2, Peng Liu2

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Acta Pharmaceutica Sinica. B
|May 14, 2016
PubMed

Keywords:
ABCA1ABCA1, ATP-binding cassette transporter A1ABCG1ABCG1, ATP-binding cassette transporter G1ApoA-I, apolipoprotein A-IAtherosclerosisCholesterol effluxGAPDH, glyceraldehyde-phosphate dehydrogenaseHDL, high-density lipoproteinLBD, ligand-binding domainLXR, liver X receptorLXRE, LXR response elementLXRβNR, nuclear receptorRCT, reverse cholesterol transportRXR, retinoid X receptorReverse cholesterol transportox-LDL, oxidized low-density lipoprotein

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