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Updated: Mar 21, 2026

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
Published on: July 12, 2024
Emperor's new clothes: Is particle disease really infected particle disease?
Marcin K Wasko1,2,3, Stuart B Goodman4,5
1Department of Orthopaedic and Rheumoorthopaedic Surgery, The Medical Centre of Postgraduate Education, Warsaw, Poland.
Abstract:
Aseptic loosening remains the most significant long-term complication of total hip replacement. The current paradigm points to an inflammatory response to wear particles as its main trigger. Recently, there have been increasing numbers of positive bacterial isolates reported among patients with clinically absent infection. This paper reviews existing evidence on possible involvement of bacteria and microbial-associated molecular patterns in the pathology of so-called "aseptic loosening." © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1497-1504, 2016.
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