Related Experiment Video

Updated: Mar 21, 2026

Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
04:12

Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats

Published on: March 28, 2025

666

[Clinical and etiological profile malignant hypertension in children in pediatric intensive care]

D-D Batouche1, K E Kerboua2, L Sadaoui3

  • 1Service de réanimation pédiatrique CHU d'Oran, Oran, Algérie.

Annales De Cardiologie Et D'Angeiologie
|May 17, 2016
PubMed

Insights

Malignant hypertension (mHTA) is a rare but serious condition in children, often secondary to kidney issues. Early intensive care is crucial for managing severe hypertension and its organ-damaging effects in pediatric patients.

Area of Science:

  • Pediatric Nephrology
  • Pediatric Critical Care
  • Cardiovascular Research

Background:

  • Malignant hypertension (mHTA) in pediatrics presents uniquely with severe hypertension and organ damage.
  • It is a rare condition with significant implications for vital organ function in children.

Purpose of the Study:

  • To investigate the prevalence, clinical presentation, and outcomes of malignant hypertension in a pediatric intensive care setting.
  • To identify common causes and clinical signs associated with mHTA in children.

Main Methods:

  • A retrospective study analyzed pediatric intensive care cases over two 10-year periods (1994-2004 and 2005-2015).
  • Cases of malignant hypertension (mHTA) were identified and analyzed for demographic, clinical, and outcome data.

Main Results:

  • Sixty-six pediatric patients with mHTA were identified, a prevalence of 0.6%, with ages ranging from 12 months to 16 years.
  • Common manifestations included hypertensive convulsive encephalopathy (33.3%), renal disease, and severe retinopathy (stage 3/4 in 47%/51%).
  • Average blood pressure readings were 175mmHg systolic and 112.5mmHg diastolic; mHTA was frequently secondary to renal causes.

Conclusions:

  • Malignant hypertension is a rare pediatric condition characterized by severe hypertension impacting vital organs.
  • Early diagnosis and intensive care support are essential for managing pediatric mHTA and improving patient outcomes.
  • The study highlights the importance of addressing underlying causes, particularly renal disease, in pediatric mHTA.
Abstract

Keywords:
ChildEncéphalopathie hypertensive convulsivanteEnfantFOFundusHTA maligneHypertensive convulsive encephalopathyKidney injuryLésions rénalesMalignant hypertension

More Related Videos

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension09:23

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

Published on: February 11, 2017

17.7K
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.6K

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
709
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
1.2K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
4.7K
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
631
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
812
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.4K