Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of Fricke-xylenol orange-Pluronic gel dosimeters for end-to-end three-dimensional radiotherapy dosimetric quality assurance.

Physics in medicine and biology·2026
Same author

Does copper beam-hardening filtration reduce imaging dose without compromising targeting accuracy in robotic radiosurgery?

Physics in medicine and biology·2026
Same author

Experimental and computational dosimetry in an integrated workflow for remote audits in Ir-192 interstitial brachytherapy: Development and pilot implementation.

Journal of applied clinical medical physics·2026
Same author

Institution-specific pre-treatment quality assurance control and specification limits: a tool to implement a new formalism and criteria optimization using statistical process control and heuristic methods.

Physics in medicine and biology·2026
Same author

Posidonia oceanica egagropili and Magnolia grandiflora leaves as lignocellulosic substrates to enhance eumelanin production by Streptomyces nashvillensis.

New biotechnology·2025
Same author

Egocentric video analysis for automated assessment of open surgical skills via deep learning.

International journal of computer assisted radiology and surgery·2025

Related Experiment Video

Updated: Mar 21, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.8K

On source models for (192)Ir HDR brachytherapy dosimetry using model based algorithms.

Evaggelos Pantelis, Kyveli Zourari, Emmanouil Zoros

    Physics in Medicine and Biology
    |May 19, 2016
    PubMed
    Summary

    This study develops an analytical source model for (192)Ir brachytherapy sources, improving Monte Carlo dose calculations. The new model accurately predicts photon properties, enhancing efficiency and ease of use in medical physics.

    More Related Videos

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    3.3K
    Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
    10:33

    Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

    Published on: September 4, 2017

    16.7K

    Related Experiment Videos

    Last Updated: Mar 21, 2026

    Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
    06:20

    Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

    Published on: March 11, 2021

    7.8K
    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    3.3K
    Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
    10:33

    Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

    Published on: September 4, 2017

    16.7K

    Area of Science:

    • Medical Physics
    • Radiation Oncology
    • Computational Dosimetry

    Background:

    • Model-based dose calculation algorithms require accurate source models.
    • Phase space files (PHSP) and parameterized PHSP models offer efficiency improvements for Monte Carlo simulations.
    • Developing efficient and accurate source models is crucial for brachytherapy dosimetry.

    Purpose of the Study:

    • To develop and validate an analytical parameterized source model for (192)Ir brachytherapy sources.
    • To compare the accuracy of the proposed analytical model against a parameterized PHSP model and detailed Monte Carlo simulations.
    • To promote efficiency and ease of implementation in Monte Carlo-based dose calculations.

    Main Methods:

    • Generated a PHSP file for a generic (192)Ir source using Monte Carlo simulation.
    • Analyzed PHSP data to derive probability density functions (PDFs) for photon energy, position, and direction.
    • Developed an analytical parameterized source model based on source geometry and material properties.
    • Created a purely analytical source model incorporating isotropic emission and energy sampling with attenuation weighting.
    • Compared dosimetry data from detailed Monte Carlo simulations with the proposed analytical source model.

    Main Results:

    • PHSP analysis revealed 15.6% photon absorption within the source and 90.4% primary emergent photons.
    • Photon emergence was predominantly from the cylindrical source surface (98.3%), with minimal contribution from the tip (1.7%) and drive wire (0.2%).
    • The analytical parameterized source model's PDFs closely matched those of the parameterized PHSP model.
    • The purely analytical source model showed agreement better than 2% with detailed Monte Carlo dosimetry data, except near the source axis.

    Conclusions:

    • The developed analytical source model provides an accurate and efficient alternative to PHSP-based models for (192)Ir brachytherapy.
    • The model simplifies Monte Carlo-based dose calculations by eliminating the need for explicit PHSP files.
    • This work contributes to improved accuracy and accessibility of dose calculations in brachytherapy applications.