Related Experiment Video
Updated: Mar 21, 2026

Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy
Published on: September 29, 2017
Visceral adiposity index and prognosis among patients with ischemic heart failure
Patrícia Vogel1, Airton Stein2, Aline Marcadenti3
1BSc. Specialist in Clinical Nutrition, Institute of Education and Research, Hospital Moinhos de Vento (IEP/HMV), Porto Alegre, RS, Brazil.
Insights
The visceral adiposity index (VAI) may predict better outcomes in ischemic heart failure patients. Higher VAI was associated with a significantly lower risk of death in this cohort study.
Area of Science:
- Cardiology
- Obesity Research
- Prognostic Biomarkers
Background:
- The obesity paradox is recognized in heart failure, but optimal obesity indicators remain unclear.
- Identifying reliable markers is crucial for risk stratification in heart failure patients.
Purpose of the Study:
- To investigate the association between various obesity indices and mortality in heart failure patients.
- To determine if specific obesity indicators can predict prognosis in this population.
Main Methods:
- A cohort study involving 116 heart failure patients (aged 30-85) was conducted.
- Evaluated anthropometric and clinical data, calculating indices like VAI and LAP.
- Survival analyses were performed using Cox regression and Kaplan-Meier curves.
Main Results:
- Patients with ischemic heart failure who survived had higher baseline VAI compared to those who died.
- A VAI above 1.21 was associated with a 78% reduction in mortality risk (HR 0.12; P=0.02).
- Kaplan-Meier curves indicated a better prognosis for patients with higher VAI (P=0.005).
Conclusions:
- Visceral adiposity index (VAI) shows promise as a predictor of improved prognosis in ischemic heart failure.
- VAI may be a valuable tool for risk assessment and management in this patient group.
Context And Objectives:
The obesity paradox has already been established in relation to heart failure, but it is not known which obesity indicator best reflects this phenomenon. The aim of this study was to evaluate the association between obesity indexes and mortality among patients with heart failure.
Design And Setting:
Cohort study conducted in the Department of Cardiology of Hospital Nossa Senhora da Conceição (Brazil).
Methods:
Clinical, demographic, socioeconomic, biochemical and anthropometric data on 116 patients aged 30 to 85 years with a diagnosis of heart failure were evaluated. Arm fat area, body mass index, body surface area, body adiposity index, lipid accumulation product (LAP) and visceral adiposity index (VAI) were calculated. Cox regression was used to perform survival analyses.
Results:
At baseline, the individuals with ischemic heart failure who remained alive showed higher VAI (3.60 ± 3.71 versus 1.48 ± 1.58; P = 0.04) and a trend towards higher LAP, in comparison with the individuals who died. After an average follow-up of 14.3 months, ischemic heart failure patients who had VAI > 1.21 showed 78% lower risk of death (HR 0.12; 95% CI: 0.02-0.67; P = 0.02) and the Kaplan-Meier survival curves showed better prognosis for these individuals (P = 0.005; log-rank test).
Conclusion:
Our results suggest that VAI is a good predictor of better prognosis among ischemic heart failure patients.
More Related Videos
06:56Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue
Published on: July 21, 2023
10:21Evaluation of Hydration Status by Bioelectrical Impedance Vector Analysis in Patients with Ischemic Heart Disease Undergoing Exercise Stress Test
Published on: September 22, 2023
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Imaging Studies for Cardiovascular System IV: CMRI
Coronary Artery Disease III: Clinical Manifestations