Transcription Factor Drug Targets

Kostas A Papavassiliou1, Athanasios G Papavassiliou2

  • 1Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527, Athens, Greece.

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Transcription Factors02:16

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General Transcription Factors01:30

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Transcription activators are proteins that promote the transcription of genes from DNA to RNA. In most cases, these proteins contain two separate domains ‒ a domain that binds to DNA and a domain for activating transcription; however, in some cases, a single domain is responsible for both binding and activation of transcription, as seen in the glucocorticoid receptor and MyoD.
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