Echocardiographic measures of atrial function may predict atrial fibrillation in stroke patients

David Waldenhjort1,2, Piotr Sobocinski Doliwa1, Mahbubul Alam1

  • 1a Department of Clinical Sciences, Karolinska Institutet , Danderyd University Hospital Stockholm , Sweden ;

Insights

Echocardiography can predict undiagnosed atrial fibrillation (AF) in stroke patients. Left atrial volume index and tissue Doppler imaging measures of atrial contraction effectively identify silent AF.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Imaging

Background:

  • Atrial fibrillation (AF) is a common cause of stroke, necessitating anticoagulant therapy.
  • Identifying undiagnosed AF in stroke patients is crucial for effective stroke prevention.

Purpose of the Study:

  • To evaluate the predictive value of echocardiography for detecting unknown atrial fibrillation (AF) in patients with a history of stroke or transient ischemic attack (TIA).

Main Methods:

  • A prospective study involving 174 stroke/TIA patients without diagnosed AF.
  • Echocardiographic evaluation included tissue Doppler imaging (TDI) to assess left atrial and left ventricular diastolic function.
  • AF screening was conducted over a 30-day period.

Main Results:

  • Fifteen patients (8.6%) were diagnosed with AF.
  • Patients with AF exhibited larger left atrial volume index (LAVI) and lower A' velocities compared to those without AF.
  • Echocardiographic parameters like LAVI and LAVI/A' ratios demonstrated significant predictive value for detecting AF (AUC 0.71-0.78).

Conclusions:

  • Left atrial volume index (LAVI) and atrial contraction measures via TDI can predict undiagnosed AF in post-stroke/TIA patients.
  • These echocardiographic findings may aid in the detection of silent AF, guiding anticoagulant treatment decisions.
Abstract

Related Concept Videos

Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
464
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
407
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
826
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
868
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
953