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Updated: Jun 3, 2026

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Apnea attacks in infants: study of 7 cases]
M Baca Cots1, G Milano Manso, C Calvo Macías
1Departamento de Pediatría, Hospital Regional Carlos Haya, Malaga.
Anales Espanoles De Pediatria
|February 1, 1989
Summary
This study investigated unexplained apneic spells in infants. Gastroesophageal reflux and hyponatremia were identified as key diagnoses in these cases.
Area of Science:
- Pediatrics
- Neonatology
- Gastroenterology
Background:
- Apneic spells in young infants can present diagnostic challenges.
- Identifying the underlying etiology is crucial for appropriate management and improved outcomes.
Observation:
- Seven infants with unexplained apneic spells were evaluated.
- Two infants with severe apnea showed signs of gastroesophageal reflux.
- Other infants presented with hyponatremia, cytomegalic inclusion disease, or prematurity-related apnea.
Findings:
- Gastroesophageal reflux was diagnosed in two infants with severe apneic spells.
- Hyponatremia was identified as a contributing factor in some cases.
- Infectious (e.g., RSV) and congenital factors (e.g., cytomegalic inclusion disease) were also considered.
Implications:
- Gastroesophageal reflux should be considered in the differential diagnosis of unexplained infant apnea.
- Prompt diagnosis and management of underlying conditions like reflux and hyponatremia are essential.
- Further research may elucidate the complex interplay of factors contributing to infant apnea.
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