Related Experiment Video
Updated: Mar 20, 2026

A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia
Published on: November 14, 2020
Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration
María I Herrera1, Rodolfo Kölliker-Frers2, George Barreto3
1Instituto de Investigaciones Cardiológicas, Facultad de Medicina, Universidad de Buenos Aires - Consejo Nacional de Investigaciones Científicas y TécnicasBuenos Aires, Argentina; Centro de Investigaciones en Psicología y Psicopedagogía, Facultad de Psicología, Universidad Católica ArgentinaBuenos Aires, Argentina.
Abstract:
Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.
More Related Videos
09:19Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
Published on: December 8, 2017
08:52Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
Published on: January 10, 2018
Related Concept Videos
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
Neurogenesis and Regeneration of Nervous Tissue
Glial Cells