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Related Concept Videos

Vision01:24

Vision

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Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
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Thalamic Visual Prosthesis.

Hieu T Nguyen, Siva M Tangutooru, Corey M Rountree

    IEEE Transactions on Bio-Medical Engineering
    |May 24, 2016
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    Summary
    This summary is machine-generated.

    This review advocates for a visual prosthesis targeting the lateral geniculate nucleus (LGN) in glaucoma patients. The LGN

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    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Biomedical Engineering

    Background:

    • Glaucoma is a neurological disorder causing blindness via retinal ganglion cell and subsequent visual pathway neuron loss.
    • Current research explores visual prostheses targeting the visual cortex or lateral geniculate nucleus (LGN) for glaucoma patients.

    Purpose of the Study:

    • To present a case for the LGN as a superior target for visual prostheses in glaucoma.
    • To review existing research on thalamic visual prostheses and identify clinical application gaps.

    Main Methods:

    • Literature review of existing research on visual prostheses and thalamic stimulation.
    • Analysis of the anatomical and structural properties of the LGN relevant to neural prosthetics.

    Main Results:

    • The LGN's compact and orderly structure presents advantages over the visual cortex for visual prosthesis implantation.
    • Significant gaps exist in current research hindering clinical translation of thalamic visual prostheses.

    Conclusions:

    • The LGN is a promising target for visual prostheses to restore vision in glaucoma.
    • Further research is needed to address technological challenges and the impact of LGN neuron loss in advanced glaucoma.