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Published on: December 21, 2018
Dismounted Complex Blast Injuries Including Invasive Fungal Infections
Clinton K Murray1, Kirby Gross, Robert J Russell
1US Army Medical Department Center and School, JBSA Fort Sam Houston, Texas.
Abstract:
Large blast injuries during dismounted operations in southwest Afghanistan causing major limb amputations and perineal injuries associated with large blood volume resuscitation were associated with invasive fungal, primarily mold, infections. This article outlines the interventions undertaken to mitigate excess morbidity and mortality associated with invasive fungal infection. These interventions include defining the problem and associated risk with systemically collected and analyzed information, developing improved protective body armor for the thigh and perineal region, standardizing management through clinical practice guidelines that outlined risk, diagnostic and treatment recommendations with enhanced discussions on the weekly Theater Combat Casualty Care Conference that includes personnel from the combat zone, Germany, and the United States. The article concludes by explaining the key way forward with regarding an inner-war approach to sustained knowledge and skills.
Insights
Combat injuries involving amputations and perineal wounds led to invasive fungal infections. Interventions focused on risk assessment, protective gear, and standardized clinical guidelines to reduce combat casualty mortality.
Area of Science:
- Military medicine
- Infectious disease epidemiology
- Trauma surgery
Background:
- Large blast injuries in Afghanistan operations resulted in major limb amputations and perineal trauma.
- High-volume blood resuscitation in these casualties correlated with invasive fungal infections, predominantly molds.
Purpose of the Study:
- To outline interventions aimed at mitigating morbidity and mortality from invasive fungal infections in combat casualties.
- To detail strategies for managing and preventing fungal infections in deployed military personnel.
Main Methods:
- Systematic data collection and analysis to define the problem and associated risks.
- Development of enhanced protective body armor for the thigh and perineal areas.
- Standardization of management through clinical practice guidelines and multidisciplinary case conferences.
Main Results:
- Implementation of a comprehensive strategy addressing risk identification, protective measures, and standardized treatment protocols.
- Improved communication and knowledge sharing through the Theater Combat Casualty Care Conference.
Conclusions:
- A multi-faceted approach involving risk assessment, technological advancements (body armor), and standardized clinical guidelines is crucial.
- Sustained knowledge and skills through an "inner-war" approach are vital for long-term management of combat-related fungal infections.
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