Related Experiment Video
Updated: Mar 20, 2026

07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
16.6K
Blepharoptosis and hypertrophic osteoarthropathy: A case report
Aysun Sanal Dogan1, Gölge Acaroglu2, Ozlem Dikmetas3
1Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Indian Journal of Ophthalmology
|May 26, 2016
Summary
Secondary hypertrophic osteoarthropathy (HOA) can manifest with eyelid complications, not just typical symptoms. Comprehensive systemic and pathological evaluation is crucial, especially after unsuccessful blepharoptosis surgery.
Area of Science:
- Ophthalmology
- Rheumatology
- Oncology
Background:
- A 52-year-old male with secondary hypertrophic osteoarthropathy (HOA) presented with blepharoptosis.
- The patient also exhibited finger clubbing, hyperhidrosis, and hypertrichosis, alongside a history of abdominal neoplasia and myelolipoma.
Observation:
- The patient underwent upper eyelid reconstruction, including blepharoplasty, wedge resection, and brow suspension for ptosis.
- Despite surgical intervention, the underlying cause of the eyelid involvement remained a concern.
Findings:
- This case highlights that eyelid abnormalities can be an atypical manifestation of hypertrophic osteoarthropathy (HOA).
- Routine blood work did not reveal significant abnormalities, underscoring the need for broader diagnostic considerations.
Implications:
- Eyelid involvement should be considered in the differential diagnosis of HOA, prompting thorough systemic and pathological investigations.
- Emphasizes the importance of a holistic patient evaluation, particularly when blepharoptosis surgery yields suboptimal results, to identify potential underlying systemic conditions like HOA.

