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Data on IL-17 production induced by plant lectins

Thiago Aparecido da Silva1, Fabrício Freitas Fernandes1, Maria Cristina Roque-Barreira1

  • 1Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.

Data in Brief
|May 26, 2016
PubMed

We reported in article da Silva et al. (2016) [2] that ArtinM induces the IL-17 production through interaction with CD4(+) T cells and stimulation of IL-23 and IL-1. Besides ArtinM, other plant lectins (PLs) induce IL-17 production by murine spleen cells. The IL-17 production induced by PLs was evaluated regarding the involvement of IL-23, IL-6, Th1-, and Th2-cytokines. Furthermore, the effect exerted TLR2, TLR4, and CD14 on the PLs׳ performance in the induction of IL-17 was examined. The current data were compared to the known ArtinM ability to induce Th17 immunity.

Keywords:
ArtinMCarbohydrate recognitionIL-17ImmunomodulationPlant lectins

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