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Nutritional status, grip strength, and immune function in institutionalized elderly.

K Suboticanec1, A Stavljenić, L Bilić-Pesić

  • 1School of Medicine, University of Zagreb.

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
|January 1, 1989
PubMed
Summary

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Vitamin supplementation significantly improved nutrient levels and cellular immunity in institutionalized elderly. This enhanced vitamin status positively impacted immune responses, highlighting the importance of nutritional support for older adults.

Area of Science:

  • Gerontology
  • Nutritional Science
  • Immunology

Background:

  • Institutionalized elderly often exhibit deficiencies in essential vitamins and minerals.
  • Suboptimal nutritional status can negatively impact immune function and overall health in older adults.

Purpose of the Study:

  • To investigate the effects of vitamin supplementation on biochemical parameters, grip strength, and immune function in institutionalized elderly.
  • To determine the correlation between nutritional status and cellular immunity in this population.

Main Methods:

  • A group of institutionalized elderly with documented low vitamin levels received supplementation.
  • Biochemical parameters, grip strength, and delayed cutaneous hypersensitivity (a measure of cellular immunity) were assessed.
  • Statistical analysis, including stepwise regression, was used to evaluate the data.

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Main Results:

  • Vitamin supplementation led to a significant increase in biochemical vitamin levels, with all participants achieving adequate status.
  • A statistically significant positive effect was observed on delayed cutaneous hypersensitivity, indicating improved cellular immunity.
  • Nutritional status explained approximately 36% of the variability in cellular immunity (R = .599, p < 0.001).

Conclusions:

  • Vitamin and mineral supplementation effectively corrects deficiencies and improves biochemical nutritional status in institutionalized elderly.
  • Enhanced nutritional status significantly contributes to improved cellular immune function in this demographic.
  • Adequate nutrition is a critical factor influencing immune resilience in the elderly.