Astible Rivularis: Bioactive Compounds and Pharmacological Functions
Sunita Timalsena1, Prem Prasad Lamichhane2
1Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand. sunitatimalsena@ymail.com.
Chinese Journal of Integrative Medicine
|May 27, 2016
Summary
Astilbe rivularis, a rare medicinal herb, shows promise for treating various ailments. Its extracts possess antimicrobial, anti-inflammatory, and antioxidant properties, validating traditional uses.
Area of Science:
- Ethnomedicine
- Pharmacology
- Phytochemistry
Background:
- Astilbe rivularis Buch. Ham. is a rare perennial herb from the Saxifragaceae family.
- Traditionally used in the Indian subcontinent for treating ulcers, bleeding, inflammation, diarrhea, and dysentery.
Purpose of the Study:
- To review and analyze the traditional uses, pharmacological activities, and toxicological data of Astilbe rivularis.
- To validate the ethnomedicinal applications of A. rivularis based on scientific evidence.
Main Methods:
- Literature review of traditional uses, pharmacological studies, and toxicological data.
- Analysis of bioactive compounds present in A. rivularis extracts.
Main Results:
- A. rivularis extracts contain alkaloids, flavonoids, coumarins, and glycosides.
- Demonstrated biological activities include antimicrobial, anti-peptic ulcer, anti-inflammatory, and antioxidant effects.
- Toxicological studies showed mild toxicity in brine shrimp larvae but no acute toxicity in mice.
Conclusions:
- Available data support the ethnomedicinal use of A. rivularis.
- Further research is needed to identify specific bioactive compounds and elucidate their mechanisms of action for potential therapeutic applications.
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