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The Dorsoventral Patterning of Human Forebrain Follows an Activation/Transformation Model

Liankai Chi1,2,3, Beibei Fan3, Dandan Feng3

  • 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences and.

Cerebral Cortex (New York, N.Y. : 1991)
|May 27, 2016
PubMed
Summary

Human forebrain development follows an activation/transformation model. Sonic hedgehog (Shh) represses dorsal genes, releasing ventral fate in human neuroectoderm (NE).

Keywords:
Wntsbrain developmenthuman embryonic stem cellsneural differentiationregional patterningsonic hedgehog

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