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Updated: Mar 20, 2026

Subcellular Fractionation from Fresh and Frozen Gastrointestinal Specimens
Published on: July 15, 2018
Seven cases of upper gastrointestinal bleeding after cold biopsy
Khaled Alneaimi1, Ali Abdelmoula1, Magalie Vincent1
1Department of Gastroenterology, Ambroise Paré Hospital, Boulogne, France.
Background And Study Aims:
Routine biopsy of the upper gastrointestinal tract is performed with increasing frequency. It is generally considered to be safe without significant complication. However, gastrointestinal bleeding as a result of cold biopsy is a known complication. We report seven cases of upper gastrointestinal bleeding after cold biopsy and discuss clinical data, risks factors, severity and management of this event. We suggest that physicians must be more cautious with this rare but potentially severe complication.
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