Related Experiment Video
Updated: Mar 20, 2026
Using Chicken Embryo as a Powerful Tool in Assessment of Developmental Cardiotoxicities
Published on: March 21, 2021
The Effect of Stevia on the Chicken Embryo Heart
Parisa Sadighara1, Isa Mohammadpour, Mahdi Jahanbakhsh
1School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Background:
Stevioside is one of the most important food additives that has become well known for its sweetness. The aim of this study was to evaluate the impact of Stevioside on the heart.
Methods:
4-day-old embryonated chickens eggs were inoculated with Stevioside and kept until hatching. Shortly after, the heart tissue samples were taken to examine organ Oxidative stresses by measuring Malondialdehyde (MDA) and glutathione (GSH) levels, ferric reducing /antioxidant power (FRAP) and cupric ion reducing assay (CUPRIC).
Results:
There was no significant difference in glutathione level, lipid peroxidation, FRAP, and cupric assay.
Conclusion:
It was suggested that stevioside did not cause marked damages to heart tissues in chicken embryo model.
