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Body MR angiography in children: how we do it
Rajesh Krishnamurthy1,2, LaDonna Malone3, Karen Lyons4
1EB Singleton Department of Pediatric Radiology, Texas Children's Hospital, 6701 Fannin St., Suite 1280, Houston, TX, 77030, USA. rxkrishn@texaschildrens.org.
Insights
Magnetic resonance angiography (MRA) is crucial for diagnosing pediatric vascular conditions. Recent advancements enhance its effectiveness in visualizing children's vascular anatomy and pathologies.
Area of Science:
- Pediatric Radiology
- Vascular Imaging
- Magnetic Resonance Imaging
Background:
- Vascular pathologies are common in children, necessitating advanced imaging techniques.
- Magnetic resonance angiography (MRA) is a cornerstone of pediatric body imaging.
- Indications include congenital anomalies, neoplasms, and trauma.
Purpose of the Study:
- To review principles of contrast-enhanced MRA in pediatric body imaging.
- To discuss adaptations for specific clinical indications in children.
- To highlight pitfalls in post-processing and interpretation.
Main Methods:
- Focus on contrast-enhanced MR angiography techniques.
- Integration of hardware and software innovations.
- Adaptation of sequences for pediatric physiology and pathology.
Main Results:
- Recent innovations improve pediatric MRA quality and efficiency.
- Advanced techniques address diverse pediatric vascular pathologies.
- Understanding principles aids tailored imaging protocols.
Conclusions:
- Contrast-enhanced MRA is essential for pediatric vascular diagnosis.
- Technological advancements have significantly improved pediatric MRA.
- Careful application and interpretation are key for optimal outcomes.
Abstract:
Vascular pathology is ubiquitous in children. Common indications for angiographic imaging in the body include congenital anomalies, portal hypertension, assessing resectability of neoplasms, renovascular hypertension, vascular malformations, vasculitis, systemic vein thrombosis, and trauma. MR angiography, with or without the use of intravenous contrast agents, is therefore a mainstay in the repertoire of MR imaging in children. Pediatric contrast-enhanced MR angiography has benefited from several innovations in recent years, including improved hardware options like high-field-strength scanners and integrated high-density coil arrays, new sequences that combine parallel imaging, innovative k-space sampling and Dixon fat suppression with time-resolved imaging, new contrast agents with longer blood-pool residence time, and advanced post-processing solutions like image fusion. This article focuses on the principles of contrast-enhanced MR angiography of the body as it pertains to the physiologies and pathologies encountered in children. It also discusses tools to adapt the MR angiographic technique to the clinical indication, as well as pitfalls of post-processing and interpretation in commonly encountered vascular imaging scenarios in the pediatric body.
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