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Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold

Mikhail Krasavin1, Alexey Lukin2, Nikolay Zhurilo2

  • 1Institutes of Chemistry and Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russian Federation.

Bioorganic & Medicinal Chemistry
|May 28, 2016
PubMed

Keywords:
Aqueous solubilityBioisosteric replacementFFA1 agonistsFree fatty acid receptor 1GPR40Metabolic stabilityTotal polar surface areacLogP

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