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Screening and Testing in Multiples.

Mark I Evans1, Stephanie Andriole2, Shara M Evans3

  • 1Fetal Medicine Foundation of America, USA; Comprehensive Genetics, 131 East 65th Street, New York, NY 10065, USA; Mt. Sinai School of Medicine, New York, NY, USA.

Clinics in Laboratory Medicine
|May 29, 2016
PubMed
Summary
This summary is machine-generated.

Choosing between screening and invasive procedures in twin pregnancies involves weighing risks of serious disorders against procedural complications. Understanding and interpreting these risks influences decisions regarding diagnostic techniques like chorionic villus sampling.

Keywords:
AmniocentesisCVSCell-free fetal DNAFetal reductionFree β-hCGMultiple pregnancy risksPrenatal screening

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Area of Science:

  • Maternal-Fetal Medicine
  • Reproductive Genetics

Background:

  • Twin pregnancies present unique challenges for prenatal diagnosis.
  • Decisions regarding invasive procedures versus screening involve complex risk-benefit analyses.

Purpose of the Study:

  • To explore the decision-making process for prenatal testing in twin pregnancies.
  • To analyze the interpretation of risks associated with screening and invasive procedures.

Main Methods:

  • Review of current literature on prenatal screening and diagnostic techniques for twin gestations.
  • Analysis of risk perception and patient choice in the context of twin pregnancy management.

Main Results:

  • Patient choice is influenced by the perceived balance between the risk of undetected disorders and procedural complications.
  • Interpretation of statistical data significantly impacts the perceived value of different diagnostic approaches.

Conclusions:

  • The choice between screening and invasive procedures in twin pregnancies is highly individualized.
  • Clear communication and accurate interpretation of risks are crucial for informed decision-making in prenatal diagnostics for twins.