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Pyogenic vertebral osteomyelitis caused by Yersinia pseudotuberculosis.
Toshinobu Ishihara1, Masashi Miyazaki1, Toyomi Yoshiiwa1
1Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan.
Joint Bone Spine
|May 30, 2016
Summary
This report details the first documented case of pyogenic vertebral osteomyelitis caused by Yersinia pseudotuberculosis. Prompt antibiotic treatment led to a full recovery, highlighting a rare but treatable infection.
Area of Science:
- Infectious Diseases
- Microbiology
- Orthopedics
Background:
- Yersinia pseudotuberculosis is an uncommon cause of osteomyelitis, particularly vertebral osteomyelitis.
- The patient had a history of psoriasis vulgaris treated with adalimumab and consumed well water, potential risk factors.
Observation:
- A 65-year-old man presented with low back pain and fever, exhibiting elevated inflammatory markers.
- MRI revealed diffuse vertebral changes and multiple nodular lesions in the spine and iliac regions.
- Open biopsy confirmed Yersinia pseudotuberculosis in T10 and L3 vertebral lesions.
Findings:
- This is the first reported case of pyogenic vertebral osteomyelitis caused by Yersinia pseudotuberculosis.
- Yersinia pseudotuberculosis demonstrated sensitivity to a broad spectrum of antibiotics.
- The patient achieved complete recovery with antibiotic therapy, showing normalized laboratory parameters and no neurological deficits.
Implications:
- This case expands the spectrum of vertebral osteomyelitis pathogens.
- Highlights the importance of considering Yersinia pseudotuberculosis in the differential diagnosis of vertebral infections, especially in patients with relevant exposures.
- Emphasizes the efficacy of timely antibiotic intervention for a favorable prognosis.
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