Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Life Histories01:29

Life Histories

23.2K
Overview
23.2K
Autophagic Cell Death01:18

Autophagic Cell Death

4.9K
Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
4.9K
Overview of Cell Death01:30

Overview of Cell Death

10.9K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
10.9K
Necrosis01:16

Necrosis

7.2K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
7.2K
Loss of Tumor Suppressor Gene Functions01:12

Loss of Tumor Suppressor Gene Functions

6.2K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
6.2K
Apoptosis01:30

Apoptosis

16.7K
Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size...
16.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New developments in functional assessment: Probabilistic models for gold standards.

NeuroRehabilitationยท2014
Same author

Randomised clinical trial: Helicobacter pylori eradication is associated with a significantly increased body mass index in a placebo-controlled study.

Alimentary pharmacology & therapeuticsยท2011
Same author

Clinical trial: prolonged beneficial effect of Helicobacter pylori eradication on dyspepsia consultations - the Bristol Helicobacter Project.

Alimentary pharmacology & therapeuticsยท2010
Same author

Colonoscopy first for iron-deficiency anaemia.

QJM : monthly journal of the Association of Physiciansยท2007
Same author

Single-contrast small bowel enteroclysis: the province of the radiographer?

Clinical radiologyยท2004
Same author

Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis.

Alimentary pharmacology & therapeuticsยท2003
Same journal

Effect of artificial intelligence on nursing documentation and patient safety.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
Same journal

Strategies for responding to anger from patients, relatives and carers.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
Same journal

Nurses' role in detecting early and subtle signs of patient deterioration in acute hospitals.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
Same journal

Pulse oximetry: exploring its role, limitations and challenges in clinical practice.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
Same journal

Anorexia nervosa: identification and management by non-specialist nurses.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
Same journal

Skin and soft tissue abscesses: assessment and management.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)ยท2026
See all related articles

Related Experiment Video

Updated: Mar 20, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.3K

Obituary.

R F Harvey

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |May 31, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Miss Muriel Hughes, a distinguished nurse, passed away at 82. Her long career in nursing included significant contributions and leadership roles.

    More Related Videos

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
    09:41

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

    Published on: July 19, 2019

    12.2K
    Posterior Approach for Debridement of the Psoas Abscess
    06:02

    Posterior Approach for Debridement of the Psoas Abscess

    Published on: March 2, 2020

    12.2K

    Related Experiment Videos

    Last Updated: Mar 20, 2026

    Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
    03:40

    Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

    Published on: April 25, 2025

    1.3K
    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
    09:41

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

    Published on: July 19, 2019

    12.2K
    Posterior Approach for Debridement of the Psoas Abscess
    06:02

    Posterior Approach for Debridement of the Psoas Abscess

    Published on: March 2, 2020

    12.2K

    Area of Science:

    • Nursing
    • Healthcare Administration

    Background:

    • Miss Muriel Hughes had a notable career in nursing.
    • Her professional journey spanned several decades, impacting healthcare services.

    Purpose of the Study:

    • To commemorate the life and career of Miss Muriel Hughes.
    • To highlight her contributions to the nursing profession.

    Main Methods:

    • Biographical review of her career milestones.
    • Documentation of her professional qualifications and roles.

    Main Results:

    • Miss Hughes held qualifications including State Registered Nurse (SRN), State Certified Midwife (SCM), and State Trained Dental Nurse (STD).
    • She concluded her extensive and respected nursing career in Bournemouth.

    Conclusions:

    • Miss Muriel Hughes' passing marks the end of an era in nursing.
    • Her legacy is one of dedication and distinguished service in healthcare.