Related Experiment Video
Updated: Mar 20, 2026
Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
Clinical importance of bilateral disease in patients with papillary thyroid cancer
Sarah E Moore1, Katayoon Kasaian1, Steven Jones1
1From the Department of Surgery, St. Paul's Hospital and University of British Columbia, Vancouver, BC (Moore, Melck, Wiseman); the Michael Smith Genome Sciences Centre, British Columbia Cancer Research Centre, Vancouver, BC (Kasaian, Jones); and the Department of Medical Genetics, University of British Columbia, Vancouver, BC (Jones).
Abstract:
A cancer-related factor that is not included in papillary thyroid cancer (PTC) prognostic scoring systems is bilaterality. While it may seem that bilaterality should be considered during the management of PTC, its clinical importance has been debated. This controversy exists because the extent of surgery for PTC has not been found to affect survival in low-risk individuals, despite their potential for PTC bilaterality. We sought to determine if PTC bilaterality is a cancer prognosticator based upon its association with known clinical and pathological PTC prognosticators, and MACIS scores. In this article we discuss our findings and their potential clinical implications.
Related Concept Videos
01:23The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
00:59The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
01:18Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...