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Carpal tunnel syndrome in long-term hemodialyzed patients

M Corradi1, E Paganelli, G Pavesi

  • 1Institute of Clinical Orthopedics and Traumatology, University of Parma, Italy.

Journal of Reconstructive Microsurgery
|April 1, 1989
PubMed

Insights

Carpal tunnel syndrome (CTS) in hemodialysis patients is complex, influenced by AV fistulas, amyloid deposits, and dialysis duration. Incidence dramatically increases after five years of treatment.

Area of Science:

  • Nephrology
  • Neurology
  • Orthopedics

Background:

  • Carpal tunnel syndrome (CTS) is a common complication in patients undergoing long-term hemodialysis.
  • The exact etiopathology and clinical presentation in this specific population require further elucidation.

Purpose of the Study:

  • To discuss the etiopathology, clinical features, and treatment of CTS in long-term hemodialyzed patients.
  • To highlight new clinical findings and specific characteristics of CTS in this cohort.

Main Methods:

  • Review of new clinical findings related to CTS in hemodialysis patients.
  • Analysis of contributing factors including arteriovenous fistulas, beta 2 M amyloidosis, and dialysis duration.

Main Results:

  • CTS in hemodialysis patients exhibits a relatively equal sex ratio.
  • Pathogenesis is multifactorial, involving hemodynamic changes from AV fistulas, beta 2 M amyloid deposits linked to dialysis membrane biocompatibility, and a correlation with dialysis duration (years and hours/week).
  • A significant increase in CTS incidence is observed after five years of hemodialysis.

Conclusions:

  • CTS in hemodialysis patients has unique characteristics influenced by the dialysis process itself.
  • Prevention strategies for dialysis-related CTS are feasible and discussed.
  • Specific recommendations for managing and preventing CTS in hemodialyzed individuals are provided.

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