[FORMATION OF BILIODIGESTIVE AND INTERINTESTINAL ANASTOMOSES IN ENVIRONMENT OF BILIARY PERITONITIS, USING A HIGH...

Area of Science:

• Surgical Innovation
• Gastroenterology
• Biomedical Engineering

Background:

• Diffuse biliary peritonitis poses challenges for surgical reconstruction.
• Ensuring hermetic and competent anastomoses is crucial for patient outcomes.
• Traditional methods may be less effective in inflamed tissue environments.

Purpose of the Study:

• To evaluate the efficacy of high-frequency electric welding for creating anastomoses in a simulated diffuse biliary peritonitis model.
• To assess the long-term patency and integrity of welded anastomoses.
• To determine the feasibility of single-stage reconstructive surgery using welding techniques in inflamed conditions.

Main Methods:

• Diffuse biliary peritonitis was induced in 20 rabbits using Escherichia coli (E. coli) suspension and medicinal bile.
• A one-layered everting cholecystoenteroanastomosis and enteroenteroanastomosis were created using the Patonmed EKB3-300 apparatus.
• The procedure was performed 24 hours post-induction, following a Roux-en-Y configuration.

Main Results:

• Postoperative assessment at 6 months revealed no external or internal signs of the connection line.
• No evidence of anastomotic stenosis was observed.
• Welding technologies facilitated the formation of hermetic and competent biliodigestive and interintestinal anastomoses.
• Postoperative welding suture regeneration followed a typical course.

Conclusions:

• High-frequency electric welding is a viable technique for creating secure biliodigestive and interintestinal anastomoses in the challenging environment of diffuse biliary peritonitis.
• Precise conjunction of mucosal layers using welding prevents anastomotic stricture formation.
• This method enables single-stage reconstructive interventions even in severely inflamed tissues.