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Updated: Mar 20, 2026
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Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
Published on: May 7, 2019
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OCULAR SYPHILIS IN A KIDNEY TRANSPLANT RECIPIENT
Elen A Romao1, Valdes R Bolella1, Maria Estela P Nardin1
1School of Medicine, University of Sao Paulo, Ribeirao Preto, SP, Brazil.
Summary
Ocular syphilis can cause vision loss in transplant recipients. Early diagnosis and penicillin treatment are crucial for preventing serious complications and improving vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Nephrology
Background:
- Renal transplantation recipients are immunocompromised, increasing susceptibility to opportunistic infections.
- Ocular syphilis is a rare but serious manifestation of syphilis infection.
Observation:
- A renal transplant recipient presented with progressive vision loss.
- Clinical examination revealed no obvious ocular disease, but electroretinography indicated retinal ischemia.
Findings:
- Serological tests confirmed syphilis infection.
- Cerebrospinal fluid analysis revealed lymphocytic meningitis and positive syphilis serology.
- The patient experienced rapid vision improvement after penicillin treatment.
Implications:
- Ocular syphilis should be considered in transplant recipients with unexplained vision loss.
- Prompt diagnosis and treatment are essential to prevent severe visual impairment and systemic complications.
- This case highlights the importance of considering syphilis in the differential diagnosis of visual disturbances in immunocompromised patients.
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