Related Experiment Video

Updated: Mar 20, 2026

Measuring Lactase Enzymatic Activity in the Teaching Lab
04:41

Measuring Lactase Enzymatic Activity in the Teaching Lab

Published on: August 6, 2018

117.4K

Lactose and Fructose Intolerance in Turkish Children with Chronic Abdominal Pain

Ozlem Yuce1, Ayhan Gazi Kalayci, Atakan Comba

  • 1Department of Pediatric Gastroenterology, Ondokuz Mayis University, Samsun, Turkey. Correspondence to: Dr Ozlem Yuce, Ondokuz Mayis University, Faculty of Medicine, Department of Pediatric Gastroenterology, Samsun, Turkey. ozlemkirmemis@gmail.com.

Indian Pediatrics
|June 3, 2016
PubMed

Insights

Lactose intolerance and fructose intolerance are common in children with chronic abdominal pain. Dietary changes can significantly improve symptoms for these young patients.

Area of Science:

  • Pediatric Gastroenterology
  • Digestive Health
  • Clinical Nutrition

Background:

  • Chronic abdominal pain is a frequent complaint in children.
  • Identifying underlying causes like food intolerances is crucial for effective management.

Purpose of the Study:

  • To determine the prevalence of lactose and fructose intolerance in pediatric patients experiencing chronic abdominal pain.
  • To assess the link between these intolerances and functional gastrointestinal disorders.

Main Methods:

  • A cohort of 86 children with chronic abdominal pain was evaluated.
  • Hydrogen breath tests were employed to diagnose lactose and fructose malabsorption.
  • Patients met Rome III criteria for functional abdominal pain syndromes.

Main Results:

  • Lactose intolerance was diagnosed in 16.3% of the children.
  • Fructose intolerance was identified in 12.8% of the participants.
  • A significant portion of children with chronic abdominal pain exhibited these specific intolerances.

Conclusions:

  • Lactose and fructose intolerance are notable contributors to chronic abdominal pain in children.
  • Dietary modifications targeting these intolerances can lead to symptom improvement.
  • Early diagnosis and intervention are key for managing pediatric functional abdominal pain.
Abstract

More Related Videos

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport08:42

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport

Published on: November 27, 2016

11.7K
Ileectomy-induced Bile Overaccumulation in Mouse Intestine06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

10.1K

Related Concept Videos

Glucose Transporters01:27

Glucose Transporters

Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
28.0K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
851
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
893
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
1.0K
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
1.2K
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.7K