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Pain in multiple sclerosis.

D E Moulin1

  • 1Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.

Neurologic Clinics
|May 1, 1989
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) frequently causes pain, particularly chronic pain linked to myelopathy in older women with long-standing disease. Effective treatment for MS pain requires individualized approaches based on specific pain types and causes.

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Area of Science:

  • Neurology
  • Pain Medicine
  • Multiple Sclerosis Research

Background:

  • Pain is a prevalent and debilitating symptom in multiple sclerosis (MS).
  • Various acute, subacute, and chronic pain syndromes are recognized in MS patients.
  • Chronic pain in MS is often associated with myelopathy and demographic factors.

Purpose of the Study:

  • To define and characterize the different pain syndromes associated with multiple sclerosis.
  • To identify patient populations and disease characteristics linked to chronic pain in MS.
  • To outline therapeutic strategies for managing diverse MS-related pain conditions.

Main Methods:

  • Review and synthesis of existing literature on pain in multiple sclerosis.
  • Classification of pain syndromes based on onset, duration, and clinical presentation.

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  • Analysis of epidemiological data and associated factors for chronic pain.

    • Main Results:

    • Chronic pain syndromes in MS are common, particularly in women and older individuals with disease duration over 5 years.
    • Key chronic pain syndromes include dysesthetic extremity pain, back pain, and painful leg spasms.
    • Myelopathy is frequently associated with chronic pain conditions in MS.

    Conclusions:

    • Multiple sclerosis pain management necessitates a tailored therapeutic strategy.
    • Treatment selection should be guided by the specific pathophysiology of each pain syndrome.
    • A combination of pharmacologic and nonpharmacologic interventions may be employed.