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Updated: Mar 20, 2026

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Nutritional status, physical performance and disability in the elderly of the Peruvian Andes
Alessandra Tramontano1, Nicola Veronese2, Valter Giantin1
1Geriatrics Section, Department of Medicine (DIMED), University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.
Background:
Although nutritional status plays an important part in the physical performance and disability of older people, this relationship has been little studied in developing countries.
Aims:
A study on the effects of nutritional status on the physical performance and functional status of elderly people living in rural areas of the Peruvian Andes.
Methods:
The study concerned 222 people aged ≥65 years living in a rural area of the Peruvian Andes. The Mini-Nutritional Assessment (MNA) was used to classify participants as malnourished (MNA <= 17), at risk of malnutrition (MNA 18-23), or well-nourished (MNA>= 24). The short physical performance battery (SPPB) and six-minute walking test (6MWT) were used to measure participants' physical performance. Disabilities were investigated by assessing participants' self-reported difficulty in performing one or more basic activities of daily living (ADL), and instrumental activities of daily living (IADL).
Results:
The prevalence of malnutrition was 9.4 %, and more than half of our samples were at risk of malnutrition. After adjusting for potential confounders, malnourished individuals performed significantly worse than the other MNA groups in the SPPB (p for trend=0.001), 6MWT and IADL (p for trend < 0.0001 for both outcomes), but not in the ADL (p for trend = 0.23). Taking the well-nourished for reference, and after adjusting for potential confounders, malnutrition was significantly associated with disability in IADL (OR 5.36, 95 % CI 1.02-56.94; p = 0.05), and poor performance in the 6MWT (OR 2.73, 95 % CI 1.06-12.08; p = 0.03) and SPPB (OR 4.94, 95 % CI 1.01-24.07; p = 0.04).
Conclusion:
Poor nutritional status was found significantly associated with poor physical performance and poor functional status in elderly Peruvian individuals.
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