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Ocular lymphoma in two cases.

Turgay Fen

    Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
    |June 7, 2016
    PubMed
    Summary
    This summary is machine-generated.

    This report details two male patients diagnosed with primary ocular lymphoma. Both cases showed significant ocular involvement, with one diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma and the other with B-cell small lymphocytic lymphoma.

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    Area of Science:

    • Ophthalmology
    • Oncology
    • Pathology

    Background:

    • Primary ocular lymphoma is a rare malignancy affecting the eye and surrounding structures.
    • Early diagnosis and appropriate treatment are crucial for managing ocular lymphomas.

    Purpose of the Study:

    • To report two cases of primary ocular lymphoma in elderly male patients.
    • To describe the clinical presentation, diagnostic methods, and treatment outcomes for these patients.

    Main Methods:

    • Ophthalmologic examination, orbital imaging, and biopsy for histopathological diagnosis.
    • Systemic staging investigations including cranial, thoracic, and abdominal imaging.
    • Treatment with chemotherapy (cyclophosphamide, mitoxantrone, vincristine, prednisolone) and radiotherapy.

    Main Results:

    • Case 1: A 67-year-old male with conjunctival mass diagnosed with MALT lymphoma, achieving full remission after CNOP chemotherapy and radiotherapy.
    • Case 2: A 70-year-old male with retroorbital mass diagnosed with B-cell small lymphocytic lymphoma, treated with radiotherapy.

    Conclusions:

    • Primary ocular lymphoma requires a multidisciplinary approach for diagnosis and management.
    • Both MALT and B-cell small lymphocytic lymphomas can present as primary ocular malignancies with distinct clinical courses.