Ocular lymphoma in two cases

We are reporting primary ocular lymphoma in two male patients who are sixty seven and seventy years old. The first case was admitted to the hospital after an ophthalmologic examination that revealed a soft, pink homogenous vascular mass originating from the conjunctiva, and extending behind the bulbous oculi, completely covering the upper quadrant of the right eye. There was also right axial exophthalmy. Ocular adnexal and intraocular involvement was seen at physical examination and orbital imaging. Optic atrophy and retinal pigment epitheloid changes were seen at fundoscopic examination. Biopsy taken from the right eye revealed mucosa associated lymphoid tissue (MALT) lymphoma. The case was diagnosed as primary ocular adnexal and intraocular lymphoma. Left eye was normal. The cranial, thoracic and abdominal imaging examinations and other laboratory analysis were normal. He received six courses of CNOP (cyclophosphamide, mitoxantrone, vincristine, prednisolone) chemotherapy and full remission was achieved following radiotherapy. He is in full remission for two years. The second case came with proptosis and chemosis at the lower part of left eye. The cornea and anterior chamber were normal. At fundoscopy, there was superficial haemorrhage on temporal edge of discus, wide haemorrhage at the periphery of discus at the same level with parafoveal little haemorrhage focus. Orbital imaging revealed a retroorbital mass. A biopsy was done from the retroorbital mass by craniotomy. B-cell small lymphocytic lymphoma was diagnosed. Right eye was normal. He received radiotherapy.after a diagnosis of ocular adnexal lymphoma.