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Plasmacytoid dendritic cell tumor: A case report.

Füruzan Kacar Döger1, Emel Dikicioğlu Çetin, Mine Hekimgil

  • 1Department of Pathology, Faculty of Medicine, Adnan Menderes University, 00910 Aydın, Turkey Phone: +90 532 795 80 66

Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
|June 7, 2016
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Summary

A rare skin condition, plasmacytoid dendritic cell neoplasm, was identified in a 62-year-old man. This diagnosis was made despite the absence of any systemic symptoms, highlighting a unique presentation.

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Plasmacytoid dendritic cell neoplasm (PDCN) is a rare hematologic malignancy.
  • PDCN commonly presents with systemic symptoms and skin involvement.
  • Cutaneous manifestations can vary, including papules, plaques, and nodules.

Purpose of the Study:

  • To report a unique case of PDCN presenting solely with cutaneous lesions.
  • To emphasize the importance of dermatological examination in diagnosing PDCN.
  • To highlight PDCN as a differential diagnosis for unexplained skin eruptions.

Main Methods:

  • Case report of a 62-year-old male patient.
  • Clinical presentation with physical examination findings.
  • Diagnostic workup including blood chemistry and computed tomography (CT).

Main Results:

  • The patient presented with a painless eruption including erythematous plaques and purple-red papules on the trunk and extremities.
  • Blood chemistry and CT results were unremarkable.
  • Histopathological examination confirmed PDCN.

Conclusions:

  • PDCN can manifest exclusively as cutaneous lesions without systemic involvement.
  • Early recognition of dermatological signs is crucial for timely PDCN diagnosis.
  • This case expands the clinical spectrum of PDCN presentation.