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Updated: Mar 19, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Regioselective Intermolecular Diamination and Aminooxygenation of Alkenes with Saccharin
Claudio Martínez1, Edwin G Pérez1,2, Álvaro Iglesias1
1Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.
Abstract:
Palladium catalysis enables the regioselective difunctionalization of alkenes using saccharin as the nitrogen source in the initial step of aminopalladation. Depending on the reaction conditions, diamination or aminooxygenation pathways can be accessed using hypervalent iodine reagents as the terminal oxidants. The aminooxygenation of allylic ethers originates from an unprecedented ambident behavior of saccharin. The participating palladium catalysts contain a palladium-saccharide unit. Two representative complexes of this type could be isolated and characterized.
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