Related Experiment Video
Updated: Mar 19, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Effects of heat acclimation on hand cooling efficacy following exercise in the heat
Elizabeth L Adams1,2, Lesley W Vandermark1, J Luke Pryor1,3
1a Korey Stringer Institute, Human Performance Laboratory, Department of Kinesiology , University of Connecticut , Storrs , CT , USA.
Abstract:
This study examined the separate and combined effects of heat acclimation and hand cooling on post-exercise cooling rates following bouts of exercise in the heat. Seventeen non-heat acclimated (NHA) males (mean ± SE; age, 23 ± 1 y; mass, 75.30 ± 2.27 kg; maximal oxygen consumption [VO2 max], 54.1 ± 1.3 ml·kg-1·min-1) completed 2 heat stress tests (HST) when NHA, then 10 days of heat acclimation, then 2 HST once heat acclimated (HA) in an environmental chamber (40°C; 40%RH). HSTs were 2 60-min bouts of treadmill exercise (45% VO2 max; 2% grade) each followed by 10 min of hand cooling (C) or no cooling (NC). Heat acclimation sessions were 90-240 min of treadmill or stationary bike exercise (60-80% VO2 max). Repeated measures ANOVA with Fishers LSD post hoc (α < 0.05) identified differences. When NHA, C (0.020 ± 0.003°C·min-1) had a greater cooling rate than NC (0.013 ± 0.003°C·min-1) (mean difference [95%CI]; 0.007°C [0.001,0.013], P = 0.035). Once HA, C (0.021 ± 0.002°C·min-1) was similar to NC (0.025 ± 0.002°C·min-1) (0.004°C [-0.003,0.011], P = 0.216). Hand cooling when HA (0.021 ± 0.002°C·min-1) was similar to when NHA (0.020 ± 0.003°C·min-1) (P = 0.77). In conclusion, when NHA, C provided greater cooling rates than NC. Once HA, C and NC provided similar cooling rates.
Related Concept Videos
Responses to Heat and Cold Stress
Body Temperature
Body Temperature
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
Requirements for Human Life
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Mechanism of heat transfer
Mechanisms of Heat Transfer
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant...

