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Updated: Mar 19, 2026

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
[Goodpasture Syndrome: a Rare Cause of Acute Anuric Renal Failure]
Dirk Bareiss1, Helmut Hopfer2, Thomas Menter2
11 Klinik für Transplantationsimmunologie und Nephrologie, Universitätsspital Basel.
Abstract:
We report a case of a 68 year old male who presented with an acute onset of anuric renal failure. Investigations revealed a histologically confirmed “double-positive” anti-GBM disease with initially undetectably high antibody values. An induction therapy with plasma exchange, cyclophosphamide and initially high dose steroids and further maintenance therapy for three months was initiated. The patient remained dialysis-dependent despite partial recovering of renal function. Without pulmonary involvement there were no clues for Goodpasture’s disease. Renal prognosis is unfavourable.
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