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Biochemical Engineering Approaches for Increasing Viability and Functionality of Probiotic Bacteria
Huu-Thanh Nguyen1,2, Dieu-Hien Truong3, Sonagnon Kouhoundé4
1Natural Products and Industrial Biochemistry Research Group (NPIB), Faculty of Applied Sciences, Ton Duc Thang University, 19 Nguyen Huu Tho, Tan Phong Ward, District 7, 700000 Ho Chi Minh City, Vietnam. nguyenhuuthanh@tdt.edu.vn.
International Journal of Molecular Sciences
|June 9, 2016
Summary
Improving probiotic bacteria viability is crucial for health benefits. This review explores using controlled sub-lethal stress to enhance probiotic robustness and functionality for industrial applications.
Area of Science:
- Microbiology
- Biotechnology
- Food Science
Background:
- Growing evidence supports probiotics' health benefits.
- Probiotic consumption is increasing globally.
- Challenges exist in maintaining probiotic viability and functionality.
Purpose of the Study:
- To review methods for enhancing probiotic viability and functionality.
- To explore the use of sub-lethal stress for microbial robustness.
- To discuss industrial-scale implementation of these methods.
Main Methods:
- Literature review of technological tools for probiotic improvement.
- Analysis of microbial adaptation to controlled sub-lethal stress.
- Case study using Bifidobacterium bifidum.
Main Results:
- Sub-lethal stress can enhance microbial robustness and viability.
- Specific stress conditions can improve probiotic functionality.
- Industrial implementation requires overcoming technical challenges.
Conclusions:
- Controlled stress application is a promising strategy for improving probiotics.
- Further research is needed for industrial-scale application.
- Simultaneous enhancement of viability and functionality is achievable.
Keywords:
biochemical engineeringcellular robustnessexopolysaccharideprebioticsprobioticssub-lethal stresssurvivalMore Related Videos
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