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Updated: Mar 19, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
Published on: January 7, 2018
Intrauterine thrombosis of umbilical artery - case report
Gustavo Henrique de Oliveira1, Cristiane de Moraes Dias2, Denise Cristina Mós Vaz-Oliani3
1MD, MSc. Visiting Professor, Interdepartmental Centre for Fetal Medicine, Faculdade de Medicina de São José do Rio Preto (FAMERP), and Attending Physician, Instituto de Medicina Reprodutiva e Fetal SS (IMR), São José do Rio Preto, SP, Brazil.
Context:
Umbilical cord thrombosis is related to greater fetal and perinatal morbidity and mortality. It is usually associated with umbilical cord abnormalities that lead to mechanical compression with consequent vascular ectasia. Its correct diagnosis and clinical management remains a challenge that has not yet been resolved.
Case Report:
This study reports a case of umbilical artery thrombosis that occurred in the second half of a pregnancy. The umbilical cord was long, thin and overly twisted and the fetus presented severe intrauterine growth restriction. The clinical and histopathological findings from this case are described.
Conclusions:
This case report emphasizes the difficulty in diagnosing and clinically managing abnormalities of intrauterine life with a high chance of perinatal complications.

