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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Language and Cognition01:27

Language and Cognition

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Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
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Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
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Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Learning Disabilities01:25

Learning Disabilities

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Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
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Related Experiment Video

Updated: Mar 19, 2026

A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice
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[Dementia with motor and language disorders].

Assal Frédéric, Joseph Ghika

    Revue Medicale Suisse
    |June 10, 2016
    PubMed
    Summary

    Alzheimer's disease and dementias involve more than memory loss, often including complex motor and language deficits. Recognizing these symptoms is crucial for diagnosing neurodegenerative diseases.

    Area of Science:

    • Neurology
    • Neuroscience
    • Clinical Medicine

    Context:

    • Alzheimer's disease and other dementias present with diverse cognitive and motor symptoms beyond memory impairment.
    • Neurodegenerative diseases frequently manifest with complex motor signs and distinct language deficits.

    Purpose:

    • To review parkinsonism in diffuse Lewy Body Disease and related neurodegenerative conditions.
    • To describe primary progressive aphasia and its variants, including clinical evaluation.
    • To highlight the significance of motor and language syndromes in diagnosing neurodegenerative diseases.

    Summary:

    • This review examines parkinsonism in diffuse Lewy Body Disease and motor deficits in frontotemporal dementia spectrum disorders.
    • It details primary progressive aphasia and its variants, emphasizing clinical evaluation.

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  • Complex motor and language syndromes are key diagnostic criteria and phenotypical markers for neurodegeneration.
  • Impact:

    • Enhances clinical practice by providing insights into diagnosing neurodegenerative diseases.
    • Improves understanding of phenotypical markers in neurodegeneration.
    • Contributes to the differential diagnosis of dementias and related neurological disorders.