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Related Concept Videos

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Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
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Protists are diverse eukaryotic microorganisms that lack the specialized tissues of plants and animals and the chitinous cell walls of fungi. Their early divergence within Eukarya resulted in structural, functional, and ecological diversity. They are classified into supergroups such as Archaeplastida, Excavata, Amoebozoa, Rhizaria, Alveolata, and Stramenopiles, determined through genetic analysis and structural similarities.Structural and Functional AdaptationsProtists have various adaptations...
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Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
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Related Experiment Video

Updated: Mar 19, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
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Malaria: Global progress 2000 - 2015 and future challenges.

Richard E Cibulskis1, Pedro Alonso2, John Aponte2

  • 1Global Malaria Programme, World Health Organization, 20 avenue Appia, 1211, Geneva 27, Switzerland. cibulskisr@who.int.

Infectious Diseases of Poverty
|June 11, 2016
PubMed
Summary
This summary is machine-generated.

Significant global progress has been made in reducing malaria incidence and mortality since 2000, driven by increased funding and expanded interventions like insecticide-treated nets and diagnostics. However, accelerated efforts are crucial in high-burden countries to meet future malaria targets.

Keywords:
Burden of diseaseEliminationMDGMalariaMonitoring and evaluationPovertySDGSurveillanceUniversal health coverage

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Area of Science:

  • Global Health
  • Infectious Disease Epidemiology
  • Public Health Interventions

Background:

  • The World Health Assembly set malaria control targets for 2015, aiming to reduce disease incidence and mortality.
  • Significant financial investment and expanded program coverage have transformed malaria control efforts since 2000.
  • These advancements have led to a substantial decrease in the global burden of malaria.

Discussion:

  • Between 2005 and 2014, investments in malaria programs more than doubled, funding expanded prevention, diagnostics, and treatment.
  • Insecticide-treated nets, rapid diagnostic tests, and antimalarial medicines have become more accessible, improving patient outcomes.
  • Malaria incidence and mortality have decreased by 37% and 60% globally since 2000, respectively, with interventions accounting for 70% of case reductions in sub-Saharan Africa.

Key Insights:

  • Malaria incidence and mortality reductions have been observed globally, but progress is slowest in countries with the highest disease burden.
  • Achieving future malaria targets necessitates accelerated reductions in incidence within these high-burden nations.
  • Malaria control is hampered by its concentration in low-resource settings with limited capacity for health system improvements.

Outlook:

  • Malaria interventions are highly cost-effective, saving substantial public health funds and reducing disease burden.
  • Continued investment in malaria programs contributes to Sustainable Development Goals and improves the well-being of vulnerable populations.
  • Accelerated progress in high-burden countries is essential for achieving global malaria eradication goals.