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Updated: Aug 18, 2026

Methods to Study Epithelial Transport Protein Function and Expression in Native Intestine and Caco-2 Cells Grown in 3D
Published on: March 16, 2017
[The hormone-cyclase system and its possible role in disorders of the absorptive function of the intestines]
Abstract:
The correlation between intestinal resorption and changes in hormone (gastrin, insulin, triiodothyronine, ACTH and cortisol) and cyclic nucleotide secretion was examined in 53 patients with chronic enteritis. Blood hormone and cyclic nucleotide levels were measured by radioimmunoassay. Intestinal activity was assessed by combined diagnostic tests. Most patients with impaired small-intestinal resorption showed considerable changes in hormonal and cyclic nucleotide levels. Abnormal operation of the hormone-cyclase system may be related to changed levels of both the hormones and cyclic nucleotides. The results of the study may be useful for the understanding of the pathogenesis as well as the diagnosis of intestinal resorption disorders in patients with chronic enteritis.
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