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[Changes in anti-oxidative homeostasis in hemodialysis patients]
S Schmidtmann1, I Popov, K Precht
1Klinik für Innere Medizin, Bereiches Medizin (Charité) der Humboldt-Universität zu Berlin.
Zeitschrift Fur Urologie Und Nephrologie
|February 1, 1989
Abstract:
Changes of the antioxidative homoeostasis in hemodialysis patients were registered by determination of the antioxidative capacity (AC). This capacity has been increased before dialysis and decreased by 50% during dialysis. After 30 minutes of dialysis the AC was much more decreased than creatinine and urea. The cause of this AC reduction is not only a loss of antioxidants into the dialysate, but possibly also an oxygen radical formation by C5a-activated granulocytes, sequestered in pulmonary capillaries during transient leucopenia.