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Recent Research in the Genetics of Exercise Training Adaptation
The genetic basis for exercise training adaptation remains largely unknown. Despite extensive research, identifying specific genes influencing individual responses to exercise is an ongoing challenge.
Area of Science:
- Exercise immunology
- Human genetics
- Sports medicine
Background:
- Research on the genetic factors influencing exercise training adaptations has intensified since 2009.
- Understanding genetic polymorphisms associated with exercise response variability is crucial for personalized training.
Purpose of the Study:
- To review and evaluate the current literature on genetic aspects of exercise training adaptation.
- To identify specific genes and genetic combinations linked to interindividual variability in exercise responses.
Main Methods:
- Systematic literature review focusing on studies published since 2009.
- Analysis of research examining genetic polymorphisms and their association with exercise-related traits.
Main Results:
- Few large-scale studies exist, limiting conclusive identification of genetic factors.
- Associations between genetic polymorphisms and variability in aerobic fitness, hemodynamics, metabolism, body composition, and muscular traits are explored.
Conclusions:
- The precise genetic underpinnings of exercise training adaptations are not yet fully elucidated.
- Continued research, particularly large-scale studies, is necessary to identify specific genetic contributors to exercise response variability.
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