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Updated: Mar 19, 2026

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Bioluminescent Bacterial Imaging In Vivo
Published on: November 4, 2012
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A versatile two-photon fluorescent probe for ratiometric imaging E. coliβ-galactosidase in live cells and in vivo
Xue-Xiang Zhang1, Hao Wu, Peng Li
1State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS), Dalian 116023, P. R. China. klhan@dicp.ac.cn.
Abstract:
We have described the design, synthesis, spectroscopy and biological applications of NI-βGal, a versatile fluorescent probe to detect E. coliβ-galactosidase in live cells and mice sensitively and directly, which holds great promise for its application in biomedical research such as gene therapy for cancer in the future.

