Related Experiment Video
Updated: Mar 19, 2026
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis
Biplab Das1, Manoj Kumar Goyal1, Manish Modi1
1Department of Neurology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Punjab and Haryana, India.
Objectives:
Subacute sclerosing panencephalitis (SSPE) is rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection with measles virus. No cure for SSPE exists, but the condition can be managed by medication if treatment is started at an early stage.
Methods And Results:
Heterogeneity of imaging findings in SSPE is not very uncommon. But pial and gyral enhancements are very rarely noticed. Significant asymmetric onset as well as pial-gyral enhancements is not reported. Herein we present a case of 16 years adolescent of SSPE having remarkable asymmetric pial-gyral enhancements, which were misinterpreted as tubercular infection.
Conclusion:
Early diagnosis and treatment is encouraging in SSPE, although it is not curable with current therapy. Clinico-radiological and electrophysiological correlation is very important in diagnosis of SSPE, more gravely in patients having atypical image findings as in our index case.
