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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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A collaborative approach to develop a multi-omics data analytics platform for translational research.

Axel Schumacher1, Tamas Rujan1, Jens Hoefkens2

  • 1Genedata AG, Margarethenstrasse 38, 4053 Basel, Switzerland.

Applied & Translational Genomics
|June 14, 2016
PubMed
Summary
This summary is machine-generated.

Researchers can now integrate and analyze large datasets in translational research more effectively. A new unified platform combines knowledge management and data analysis for secure, collaborative R&D projects.

Keywords:
Data analyticsData sharingIntegrationOmicsScalabilityTranslational research

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Area of Science:

  • Biomedical Informatics
  • Translational Research
  • Data Science

Background:

  • Integrating and analyzing large datasets is a significant challenge in translational research.
  • Existing systems often have gaps between data collection and data exploitation.

Purpose of the Study:

  • To propose a collaborative approach for integrating data management and analytical systems.
  • To address data security and support distributed research teams.
  • To demonstrate a unified platform for efficient data handling in translational R&D.

Main Methods:

  • Developed a collaborative framework integrating data management (tranSMART) and analytical systems (Genedata Analyst™).
  • Implemented a unified, end-to-end platform.
  • Focused on ensuring data security and supporting distributed teams.

Main Results:

  • Successfully implemented a unified platform combining tranSMART and Genedata Analyst™.
  • The platform facilitates quick data finding, entry, integration, analysis, extraction, and sharing.
  • Enhanced efficiency in handling patient- and drug-related data for R&D.

Conclusions:

  • The unified platform effectively bridges the gap between data collection and exploitation in translational research.
  • This approach enhances data security and collaboration for distributed research teams.
  • The integrated system accelerates the R&D process by streamlining data management and analysis.