Infections Associated with Streptococcus intermedius in Children

Howard S Faden1

  • 1From the Division of Infectious Diseases, Department of Pediatrics, University of Buffalo School of Medicine, Women and Children's Hospital, Buffalo, New York.

Insights

Streptococcus intermedius bacteria caused serious abscesses in 48 children over seven years, often leading to severe illness. Most infections occurred seasonally in older children, highlighting a need for awareness.

Area of Science:

  • Microbiology
  • Pediatric Infectious Diseases

Background:

  • Streptococcus intermedius is a bacterium within the viridans group, specifically the Anginosus group.
  • This bacterium has been increasingly recognized for its association with various infections.

Purpose of the Study:

  • To analyze the clinical characteristics and trends of infections caused by Streptococcus intermedius in pediatric patients.
  • To identify risk factors and seasonal patterns associated with Streptococcus intermedius-related abscesses in children.

Main Methods:

  • Retrospective analysis of pediatric cases associated with Streptococcus intermedius.
  • Review of medical records to determine infection severity, causative role of the pathogen, and demographic data.

Main Results:

  • Over a 7-year period, 48 children were diagnosed with Streptococcus intermedius-associated abscesses.
  • Forty percent of these children experienced complicated or life-threatening illnesses.
  • Streptococcus intermedius was the sole pathogen identified in 35 of the cases.
  • Infections predominantly occurred during winter and spring (75% of cases).
  • No infections were reported in children younger than 1 year.

Conclusions:

  • Streptococcus intermedius represents a significant pathogen causing severe and complex abscesses in children.
  • The seasonal predilection for winter and spring suggests potential environmental or behavioral factors influencing transmission.
  • Clinical vigilance is warranted for this bacterium, particularly in children over one year of age presenting with abscesses.

Related Concept Videos

Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
3.0K
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
4
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.4K
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
5.4K
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
706
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.1K